I like this question. I have never had a a one night stand as it's not my thing, I lost my V card to a friends with benefits situation to a wonderful man I met on a fetish site (that is the only fwb situation I had) and I have had two long term relationships (outside of the hobby). I think at the end of the day the difference in quality and intimacy boils down to chemistry regardless of the "relationship". For example one of my long term relationships was a bit of a joke

most of the time there was no real quality or intimacy, a lot of the time it felt forced, going through the motions of being in a "serious relationship". The other one however was great, every time we were "together" felt energized, passionate, carnal and liberating. I have been with men in the hobby that didn't like kissing, talking, cuddling or the lights on... safe to say I could have been any ransom lady and it wouldn't have made a difference, then there are the gents that made me feel as if I could fly, the ones that text me later and with just a message I am tingling in anticipation. Then of course the fwb, maybe bias as he was my first, but every time was new and exciting even the things we had already done, every touch electric and every smile or eye twinkle exhilarating! So do I feel a difference in quality and intimacy basised on the circumstances of our meeting, no I do not, I notice a difference on whether we have chemistry and whether we were simply just meant to be "entangled". I look forward to reading other thoughts on the matter
Xo
Katey