Here's some more stuff with DATY AND BBBJ
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Bronco wouldn't never DATY on any of them or have BBBJ
Mycoplasma pneumoniae
Today, M.pneumoniae remains an important cause of pneumonia and other airway disorders such as tracheobronchitis and pharyngitis. This organism is also associated with extrapulmonary manifestations such as hematopoietic, joint, central nervous system, liver, pancreas and cardiovascular syndromes.
Mycoplasma genitalium
M.genitalium was originally isolated from urethral specimens of two men with nongonococcal urethritis. This organism could be involved in pelvic inflammatory disease. A DNA probe hybridization assay has indicated that M.genitalium was present in urogenital specimens collected from 60% of male homosexual patients with recurrent or persistent nongonococcal urethritis and 22% of heterosexual men with recurrent urethritis, compared with 9% of men without urethritis.
Ureaplasma urealyticum
Ureaplasma urealyticum is considered to be a commensal organism in the lower genital tract of sexually-active women and has been found at a colonization rate of 40 to 80%. In some colonized pregnant women, ureaplasmas have been considered to be a cause of chorioamnionitis and premature delivery. They are frequently transmitted from mothers to their infants, and this may cause various diseases which includes pneumonia, persistent pulmonary hypertension, chronic infection of the central nervous system and bronchopulmonary dysplasia.
Mycoplasma fermentans, M. pirum, M. hominis, and M.penetrans
Mycoplasma fermentans, M. pirum, M. hominis, and M. penetrans have been proposed as human pathogens and possible cofactors in HIV infection. These organisms may contribute to the variation in the time from infection with HIV to the development of AIDS symptoms.
Mycoplasma fermentans (incognitus)
Mycoplasma fermentans is considered to be a commensal in the human mucosal tissues and has often been found in saliva and oropharyngeal of 45% of healthy adults. Also, M. fermentans organisms have been isolated from the human urogenital tract and are suspected of invading host tissues from a site of mucosal colonization.
Although mycoplasmas are recognized primarily as extracellular parasites or pathogens of mucosal surfaces, recent evidence suggests that certain species may invade the host cells.
The molecular and cellular bases for the invasion of M. fermentans from mucosal cells to the bloodstream and its colonization of blood remain unknown.
Also, it remains unclear whether M. fermentans infection of white blood cells is transient, intermittent or persistent. It is not clear how these stages influence any disease progression. The invasion of host blood cells by M. fermentans is due to inhibition of phagocytosis by a variety of mechanisms, including antiphagocytic proteins such as proteases, phospholipases and by oxygen radicals produced by mycoplasmas.
Mycoplasma fermentans is capable of fusing with lymphocytes and changing their immunological characteristics.
Mycoplasma fermentans cells are able to fuse with Tlymphocytes and change their characteristic of cytokine production. By electron microscopy we have been able to show that M. fermentans can indeed fuse with CD4 (Molt-3) cells and induce production of proinflammatory cytokines such as IL-6 and tumor necrosis factor alpha.
Prevalence of M. fermentans in patients with Chronic Fatigue Syndrome (CFS) and comparison with healthy subjects
Using PCR and genetic probes, we were able to demonstrate that between 30 and 35% of CFS patients and 4 to 8% of healthy controls do carry the Mycoplasma fermentans genome in their peripheral blood mononuclear cells.
While PCR and genetic probes are rapid and sensitive methods for detecting M. fermentans in clinical specimens, the clinical significance of this organism in Chronic Fatigue Syndrome should be determined by further research studies.
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