I love SF
I've been 4 times in the last few years.
Alcatrez is a must-do, it's award-winning, very impressive.
One of my fav resturants is Pasha:
http://www.pasharestaurant.com/
Awesome food and great atmosphere. Live Turkish band and turkish dancers with lots of customer interaction. Check out the virtual tour on the site.
Wanna do something REALLY different: Check out the Power Exchange:
http://powerexchange.com/pepnew/ It's a bizarre and kinky place where you can watch people engaging in BDSM, lots of cages and equipment, lots of theme rooms,porn playing on TV's, guys walking around jerking off, people having sex here and there...etc. Go after 11pm and bring an open mind, wear anything you want from tame to wild, you'll fit in. Very mixed crowd.
Check out the Castro. It's like our Davie St but SO much more lively. Lots of gay love, great vibe.
Awesome shopping at Haide Ashbury area for different cloths, vintage, party/stripper/sexy cloths, different stuff. No Gap here. Super fun.
The best places for fetish gear (latex, leather, corsettes, etc) Madame S and Stormy Leather.
Have a blast!